In contrast, a potential cancer-suppressing function of EFEMP1 was found in the study of nasopharyngeal carcinomas, sporadic breast cancer, glioblastoma multiforme, and non-small cell lung cancer (NSCLC), Fibulin-3 was associated with tumour progression and inhibited cell migration and invasion [25]–[28]. Here, EFEMP1 is linked to neoplasm.