A role for chemokine signalling via the chemokine receptor, CXCR3, in MS-associated neuropathic pain is supported by observations of reduced neuropathic pain behaviour in EAE-mice null for CXCR3, that was accompanied by attenuated EAE disease progression (Schmitz et al. 2013). The gene discussed is CXCR3; the disease is myeloid sarcoma.