Intriguingly, however, consistent with our model, Xia et al. [104] recently reported that exposure of the MCF7 breast carcinoma cell line to a high fluence of UVC (50 J/m2) resulted in marked upregulation of p53 coupled with suppression of not only p21, but also MDM2 and WIP1. The gene discussed is TP53; the disease is breast carcinoma.