Sox2 mRNA表达与NSCLC患者的年龄、性别、肿瘤分化程度和淋巴结转移情况无关,但与肿瘤的体积和组织学类型相关,即Sox2 mRNA在鳞癌的表达高于腺癌;Sox2 mRNA表达随肿瘤体积增高(表 1)。. The gene discussed is SOX2; the disease is non-small cell lung carcinoma.