It will be interesting to correlate the presence and frequency of molecular aberrations involving the Akt/mTOR/pS6 or other related pathways with specific OLP clinical subtypes, given that specific clinical forms of the disease (such as erosive, atrophic, and/or plaque-like OLP) have been associated with a higher malignant transformation rate [1, 2]. This evidence concerns the gene MTOR and oral lichen planus.