We demonstrate, by Western blot analysis, that miR-335 regulates the expression of at least five formin family members, three of which we validate as direct targets of miR-335: FMNL3, FMN2 and DAAM2. Furthermore, we confirm that inhibiting the expression of FMNL3, FMN2 and DAAM2 significantly reduces the motile and invasive capacity of neuroblastoma cells. Here, FMNL3 is linked to neuroblastoma.