EGFR and non-small cell lung carcinoma: Interestingly, the current study showed that the NSCLC patients with antigen-specific T cell responses to EGFR-T790M-derived epitopes showed a significantly less frequency of EGFR-T790M mutation than those without them, indicating the negative correlation between the immune responses to the EGFR-T790M-derived epitopes and presence of EGFR-T790M mutation in NSCLC patients.