The up-regulated release of IP-10/CXCL10 and IL-8/CXCL8 in patients with active pulmonary TB was suppressed by specific NF-κB inhibitor JSH-23 [42], [43], suggesting both IP-10/CXCL10 and IL-8/CXCL8 release is mediated through NF-κB activation. This evidence concerns the gene CXCL10 and pulmonary tuberculosis.