NOS3 and myocardial infarction: Scherrer-Crosbie et al. studied the impact of eNOS in left ventricular remodeling after MI in eNOS- KO mice, concluding that eNOS has a key role in limiting cardiac dysfunction and remodeling, in part by decreasing myocyte hypertrophy in the remote myocardium (Scherrer-Crosbie et al., 2001; Cannavo et al., 2013a).