MLANA and neoplasm: Exosomes secreted by tumour cells contain mRNA and proteins, among them chaperon proteins such as tetraspanins (e.g. CD9, CD63, CD81), heat-shock protein (Hsp) 70, major histocompatibility complex (MHC) class I molecules (5, 6), as well as tumour associated antigens (TAA), for instance Mart1, melan-A, gp-100 proteins, mesothelin, carcinoembryonic antigen and Her2-neu (7, 8).