As a cell-cycle regulator, RanGAP1 was also frequently overexpressed in other BCL with brisk mitotic activity (lymphoblastic lymphoma/leukemia, and Burkitt lymphoma) or cell-cycle deregulation (mantle cell lymphoma and Hodgkin’s lymphoma) [36,37], but only occasionally in low-grade BCL. This evidence concerns the gene RANGAP1 and mantle cell lymphoma.