ABCA1 and age-related macular degeneration: In 2010, two genome-wide association studies [19,20] (GWAS) reported associations of AMD with the hepatic lipase (LIPC) gene, and suggested further associations with the cholesterylester transfer protein (CETP) gene, the lipoprotein lipase (LPL) gene and the ATP-binding cassette transporter A1 (ABCA1) gene.