Importantly, in addition to the association with cognitive impairment, LOAD, and PD (this study), CNTNAP4 polymorphisms have been shown to be associated with some other phenotypes such as serum level of cholesterol and sphingolipids [32,33], glaucoma [34], autism [35], and D-amphetamine response [36]. The gene discussed is CNTNAP4; the disease is Cognitive impairment.