HFE and hemochromatosis type 1: The interesting correlations between hemochromatosis and celiac disease: a first study demonstrated that occult celiac disease prevents penetrance of hemochromatosis [21]; later, it was evidenced that the C282Y mutation of HFE gene may mitigate the severity of celiac disease [22], and finally a large case-control study concluded that hemochromatosis predispose to celiac disease [23].