In addition, two articles delineate the impact of herbal medicine and compounds on diabetic complications in animals (“Proanthocyanidin attenuation of oxidative stress and NF-κB protects apolipoprotein E-deficient mice against diabetic nephropathy” and “An aqueous extract of Radix Astragali, Angelica sinensis, and Panax notoginseng is effective in preventing diabetic retinopathy”). Here, APOE is linked to diabetic kidney disease.