Huang and colleagues (“Supplementation of Lactobacillus plantarum K68 and fruit-vegetable ferment along with high fat-fructose diet attenuates metabolic syndrome in rats with insulin resistance”) report that a mixture of fruit/vegetable ferment and one of its bacteria, Lactobacillus plantarum K68, reduced hyperglycemia, hyperinsulinemia, and hyperlipidemia as well as proinflammatory cytokines (TNF-α, IL-6, IL-1β, etc.)in HFD-induced rats. The gene discussed is IL6; the disease is Insulin resistance.