The well-known oncogenes and lymphoma-related genes that exhibited frequent breakpoints, including BCL6 (3q27), JAK2 (9p22), IGH (14q32), and BCL2 (18q21), as well as other possible oncogenes with breakpoints, are indicated in Figure 1D. Monosomal karyotypes were observed in 70 patients (46.7%), and hyperdiploidy was noted in 24 cases (16.0%). The gene discussed is BCL2; the disease is lymphoma.