In the study by Ghazala and Mansoor, they confirmed that inflammation can be implicated in the transformation of stable coronary plaque to unstable plaques, rupture and thrombus.29 Kadi et al. found in patients with stable coronary artery disease and insufficient coronary circulation, serum hs-CRP levels were higher than in patients with adequate coronary collateral circulation.30 Zhumin et al. found that the values of hs-CRP were higher in patients with unstable carotid atherosclerotic plaques than in patients with stable plaques or without plaques.31 Here, MAP3K14 is linked to coronary artery disorder.