The genes, WNT1 inducible signaling pathway protein 2 (WISP2), G protein-coupled receptor 64 (GPR64) and Tenascin XB (TNXB) were found to be upregulated in myxofibrosarcoma compared with other spindle cell and pleomorphic sarcomas. This evidence concerns the gene ADGRG2 and myxofibrosarcoma.