Agents targeting molecules such as the epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) receptor, P13k/Akt/mTor pathway, insulin-like growth factor receptor (IGFR), c-Met pathways, fibroblast growth factor receptor (FGFR) and other pathways are promising candidates for targeted therapy for GC and are now in clinical development. Here, VEGFA is linked to gastric cancer.