Several CC chemokine members, including CCL2 (MCP-1), CCL3 (MIP-1α), CCL5 (RANTES), CCL7 (MCP-3), CCL8 (MCP-2), CCL17 (TARC) CCL 20 (MIP-3α), CCL22 (MDC) and CCL23 (MPIF-1), are produced mainly by tumor infiltrating lymphocytes (TIL) and monocytes, and some of them also by cancer cells. This evidence concerns the gene CCL8 and neoplasm.