MCM2 and infectious otitis media: When fed with VPA-containing diet, Mcm2 positive rates (%) of ADCs were lower than that of the AOM and DSS group (n = 9, 80.1 ± 6.8): 125 ppm VPA (n = 7, 73.7 ± 8.0), 250 ppm VPA (n = 6, 64.2 ± 2.5, p < 0.01), and 1,000 ppm VPA (n = 5, 61.6 ± 9.6, p < 0.001).