Specifically, we have identified Tumor Necrosis Factor α (TNFα) and Interleukin 1β (IL-1β)—two inflammatory mediators that are known to be of a tumor-promoting phenotype [24,25,26,27,28,29]—as potent chemokine inducers in the present cell system, and revealed that their effects were significantly higher than those obtained by the oncogenic alterations of Ras and p53 combined. The gene discussed is TP53; the disease is neoplasm.