Augmentation of antibodies and T cells that are reactive with mono- and disaccharide constituents of TACA such as the Tn (GalNAcα-O-Ser/Thr), and Thomsen-Friedenreich (TF) (Galβ1-3GalNAcα/β-O-Ser/Thr) antigens are proposed to be of benefit for cancer survival, playing a role in immune surveillance and natural resistance to cancer [5]. This evidence concerns the gene TF and cancer.