HSPA1A and Familial prostate cancer: Interestingly, the kinetics of HSPA1A/B release induced by gamma irradiation peaked at 48 hours post exposure, whereas HSPA1A/B peaked at 24 hours in both PC-3 and DU-145 prostate cancer cells, which is indicative of a difference in the mechanism by which HSPA1A/B is transported within the cell and subsequently released into the extracellular milieu, as compared with HSPA1A/B.