SMARCB1 and rhabdoid tumor: Another example, rhabdoid tumors are largely caused by deletions or mutations of SMARCB1 (a.k.a., INI1/SNF5/BAF47), a component of the chromatin remodeling SWI/SNF complex, which functions as a tumor suppressor by modulating the cell cycle and cooperating with p53 to prevent transformation [138].