CASP8 and neuroblastoma: A range of other studies have similarly identified genes, which are methylated and silenced in neuroblastoma in various patterns, including but not limited to the tumor suppressor genes, RASSF1A and ZMYND10 (a.k.a., BLU); the angiogenesis inhibitor, THBS1 [113]; the anti-apoptotic decoy receptors, DcR1 and DcR2 [114]; the extrinsic pathway associated caspase, CASP8 [115,116], various Shh pathway genes [117]; and other factors [118-120].