In contrast to the findings of Richards and colleagues [62] we found no correlation between MUC1 IgM (or IgG) abs and age in the total population (N 456) or in the groups studied (40 healthy men, 101 healthy women, 54 nulligravidae, 45 pregnant women, 62 patients with benign breast tumors, and 154 patients with early breast cancer). The gene discussed is CD40LG; the disease is breast benign neoplasm.