EWSR1 and sarcoma: Though still presented only in abstract form at ASCO, the preliminary results of the SARC-11 trial (a multicenter, open-label, multi-arm, phase II study of R1507 for the treatment of patients with recurrent or metastatic, drug-refractory EWS and selected other sarcomas) were disappointing; this trial, and two smaller ones, exhibited treatment responses less than 9%.