Infiltration by CD4+CD25+ or CD4+FOXP3+ was correlated with poor survival in renal cell carcinomas, gastric carcinomas, breast carcinomas, ovarian carcinomas, non-small-cell lung carcinomas, melanomas and colon adenocarcinomas [65,223-232], but the presence of Treg was correlated with a greater survival in nasopharyngeal carcinoma, gastric carcinoma and lymphoma patients [71,80,84,233,234]. This evidence concerns the gene CD4 and renal cell carcinoma.