IGF1 and cancer: It is also tempting to speculate that the association of SCD1 inhibitors with nutritional interventions (i.e., high SFA diets) and/or therapeutic agents that target signaling pathways and their receptors (i.e., tyrosine-kinase-mediated cascades, such as EGFR, Her2, IGF-1, among others) may originate more effective anti-cancer treatments.