Marcato and co-workers assessed the expression of 19 ALDH isoforms and demonstrated that CSC in breast tumours could be identified using the ALDH1A3 isoform and it was shown that the expression of ALDH1A3 correlated with breast tumour grade and stage and correlated prevalence of CSC with metastatic breast cancer [72]. This evidence concerns the gene LDHA and breast neoplasm.