The median and range of the ratios of uPA mRNA measures between tumor tissue and non-involved pancreatic tissue is 17.1 (1.4–653.6) for pancreatic adenocarcinoma (P < 0.001), 3.9 (0.7–7.7), for ampullary carcinoma (P = 0.055) and 1.9 (0.6–5.9) for mucinous cystadenoma tissue (P = 0.052) [34]. This evidence concerns the gene PLAU and pancreatic adenocarcinoma.