KDM1A and colorectal carcinoma: Using cDNA microarray analysis, Hayami et al. identified KDM1A (formerly known as LSD1) as being elevated in bladder, lung and colorectal carcinomas (Table 2, Figure 1), and siRNA knockdown of KDM1 resulted in a decrease of various lung and bladder cancer cell lines, whereas overexpression promoted proliferation [112].