RIOX2 and non-small cell lung carcinoma: A JmjC containing protein called Mineral Dust-Induced Gene (MDIG)/MYC-Induced Nuclear Antigen (MINA) has been shown to be overexpressed in NSCLC and promotes ribosomal RNA (rRNA) expression through demethylation of tri-methyl lysine 9 on histone H3 at the ribosomal RNA promoter (Figure 1) [115].