FGF7 and conjunctival squamous cell carcinoma: Most importantly, Chimaka et al., have demonstrated that overexpression of FGF-7 in Keratin 12-rtTA/tet-O-FGF-7 double transgenic mouse model, in which FGF-7 expression in corneal epithelium is driven by doxycycline treatment, induces epithelial hyperplasia that mimic the human ocular surface squamous neoplasia (OSSN) [112].