In this study, in which 17 candidate markers have been evaluated by immunohistochemistry or in situ hybridization, S100A2 overexpression was the only marker significantly associated with longer overall survival [in subgroup of resected PAC, HR = 1.87; 95% CI: 1.25–2.81; p = 0.0024]. The gene discussed is S100A2; the disease is gonorrhea.