However, the difference in the number of TF + MP compared with non-cancer controls was insignificant in lung cancer (5 of 28), breast cancer (4 of 9) and ovarian cancer (5 of 8) suggesting that TF + MP have an important role in the pro-coagulant phenotype and may be a contributing factor related to the high incidence of TE associated with PC patients [29]. This evidence concerns the gene TF and breast cancer.