After correction for multiple hypotheses, the most notable pathways included Wnt signaling upregulated in the TNBC/basal-like BC subtypes of the Quebec, UNCCH-186, and Stockholm-159 cohorts; TGF-β in the TNBC subtypes of the Quebec and UNCCH-186 cohort; and both ErbB and VEGF signaling upregulated in the MSKCC-99 triple negative and UNCCH-186 basal-like subtypes (p < 0.05, Additional file 3: Figure S3). This evidence concerns the gene VEGFA and breast cancer.