In addition, hs-CRP and SAA were increased in T2DM subjects (1.74 (1.05-4.21) mg/l and 1.72 (1.13-2.57) mg/l) compared to non-diabetic subjects (1.25 (0.51-2.50) mg/l, P = 0.005 and 1.25 (0.82-1.98) mg/l, P = 0.01, respectively), but bilirubin was not significantly different between T2DM subjects (9 (7–12) μmol/l) and non-diabetic subjects 10 (7–14) μmol/l, P = 0.18). This evidence concerns the gene SAA1 and type 2 diabetes mellitus.