CXCR4 and Sepsis: It has been recently shown that reduced miR-150 serum concentrations are associated with an unfavorable outcome in critically ill patients with sepsis and it has been hypothesized that lower level of circulating miR-150 might lead to a de-repression of genes such as CXCR4 and c-Myb, that are linked to immune response activation and poor prognosis [28].