While the number of lung pDCs was mostly similar between the TLR4−/− and WT mice, with the exception of late time points of infection (Fig. 3B), the number of pDCs in MLN was significantly higher in WT mice, compare to the TLR4−/− mice, during the acute phase of infection (day 5 p.i., Fig. 3C). Here, TLR4 is linked to infection.