Similar results were obtained with baseline IL-6 and sTNFR2 remaining as independent predictors of incident cancers, with HR of 1.53 (1.18-2.00, p=0.002) per natural log unit increase in IL-6, and 3.15 (1.53-6.47, p=0.002) per natural log unit increase in sTNFR2, respectively. The gene discussed is IL6; the disease is cancer.