When array CGH analyses of the DNA tumor samples (Figure 2A) were compared with matched constitutional DNA (Figure 2B), three genomic gains were identified in regions devoid of copy number variations (CNVs) at chromosomes 6q22, 14q24 and 15q15 that include loci for NKAIN2 (Na/K transporting ATPase interacting 2), PCNX (pecanex homolog) and CASC4 (cancer susceptibility candidate 4), respectively (Figure 3 and Table 1). The gene discussed is PCNX1; the disease is cancer.