Interestingly, we found STAT3 appeared in 18 FFLs of prostate cancer (Table 5), which was significantly enriched compared to those in normal prostate tissue (chi-square test, p-value = 2.6×10−12) and in pan-cancer (chi-square test, p-value = 3.8×10−3). The gene discussed is STAT3; the disease is prostate carcinoma.