OPTN and viral infectious disease: Interestingly, this analysis revealed genes in the MAPK kinase signaling pathway (e.g., BRAF and GPS1), contributing to cell cycle regulation (e.g., FANCA, NDC80, and RB1), or coding for transcription factor subunits (e.g., AP1M1 and OPTN), all of which are known to be connected to response to virus infection and members of pathways previously implicated in our prior studies [19,20].