Finally, to better define the antioxidant response against the cytotoxic effects of oxidative stress, we evaluated the expression level of Nuclear factor-erythroid-2-related factor 2 (NRF2 or NFE2L2) and Superoxide dismutase 2, mitochondrial (SOD2) in our CKD-PD patients and HS. This evidence concerns the gene NFE2L2 and chronic kidney disease.