When muscle samples from three DM patients and four PM patients were analyzed for double labeling of eMHC and CHC22, the frequency of intense internal CHC22 immunostaining was significantly higher in eMHC-positive muscle fibers than in eMHC-negative myofibers (about 65–70% vs 10–20%, Figure 1G). Here, CLTCL1 is linked to polymyositis.