The JZL184 treatment decreased the TNF-α concentration at 24 (U = 3.0; p < 0.05) and 48 (U = 4.0; p < 0.001) hours after LPS-induced ALI (Figure 6A), as well as the IL-6 concentration at 6 (U = 2.0; p < 0.05), 24 (U = 6.0; p < 0.05) and 48 (U = 9.0; p < 0.05) hours after LPS-induced ALI (Figure 6B). Here, TNF is linked to acute respiratory distress syndrome.