SELL and acute respiratory distress syndrome: In the present study, we showed that JZL184 treatment (1) decreased the cellular expression of β2-integrin in the blood 6 hours after the LPS-induced ALI (2), increased the cellular expression of L-selectin in the blood 6 hours after the LPS instillation, and (3) decreased the cellular expression of β2-integrin in the BAL 48 hours after the induction of inflammation.