These functions might not be revealed within the 4 hours time-frame of the applied cutaneous anaphylaxis model, although MAZR-null BMMCs had approx. 50 genes dysregulated after a 4 hour FcεRI-mediated activation period in comparison to activated wt BMMCs (23 of these genes were already dysregulated in non-activated cells) (data not shown). Here, PATZ1 is linked to anaphylaxis.