Remarkably, the results from one genome-wide association study (GWAS) conducted in Chinese, in which we previously participated, identified a intron single nucleotide polymorphism (SNP) near one B regulatory subunit (PPP2R2B) to be a lung cancer susceptible locus, reflecting an important role of in PP2A on lung cancer susceptibility [23]. The gene discussed is PPP2R2B; the disease is lung cancer.