CETP and atherosclerosis: The blood pressure elevating effects of torcetrapib exert a profound influence on CETP inhibitors studies, as in RADIANCE and ILLUSTRATE (Investigating Lipid Level management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP inhibition and HDL Elevation) study, torcetrapib failed to ameliorate carotid IMT progression and increased the cause of mortality partly due to the elevated blood pressure [38].