In a previous study, we investigated the involvement of PLA2s and eicosanoids in asthma pathophysiology using a rat model of ovalbumin (OVA)-induced experimental allergic bronchitis (EAB) [4], [11], as expressed by broncho-constriction, airway remodeling, the levels of the broncho-dilator PGE2 and the broncho-constrictor Cysteinyl-LTs (CysLTs) in bronchoalveolar lavage (BAL). This evidence concerns the gene PLA2G2A and asthma.